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1

The continuous oxidation of HMF to FDCA and the immobilisation and stabilisation of periplasmic aldehyde oxidase (PaoABC).

McKenna, Shane, Mines, Paul, Law, Paul, Kovacs-Schreiner, Krisztina, Birmingham, William, Turner, Nicholas J, Leimkühler, Silke, Carnell, Andrew

Journal:

Green Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 719 KB

english, 2017

2

Dendritic Polyglycerol–Poly(ethylene glycol)-Based Polymer Networks for Biosensing Application

Dey, Pradip, Adamovski, Miriam, Friebe, Simon, Badalyan, Artavazd, Mutihac, Radu-Cristian, Paulus, Florian, Leimkühler, Silke, Wollenberger, Ulla, Haag, Rainer

Journal:

ACS Applied Materials & Interfaces

Année:

2014

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2014

3

The Role of SufS Is Restricted to Fe–S Cluster Biosynthesis in Escherichia coli

Bühning, Martin, Valleriani, Angelo, Leimkühler, Silke

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2017

4

Effect of Exchange of the Cysteine Molybdenum Ligand with Selenocysteine on the Structure and Function of the Active Site in Human Sulfite Oxidase

Reschke, Stefan, Niks, Dimitri, Wilson, Heather, Sigfridsson, Kajsa G. V., Haumann, Michael, Rajagopalan, K. V., Hille, Russ, Leimkühler, Silke

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2013

5

Catalytic bio–chemo and bio–bio tandem oxidation reactions for amide and carboxylic acid synthesis

Bechi, Beatrice, Herter, Susanne, McKenna, Shane, Riley, Christopher, Leimkühler, Silke, Turner, Nicholas J., Carnell, Andrew J.

Journal:

Green Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 222 KB

english, 2014

6

The biosynthesis of the molybdenum cofactors

Mendel, Ralf R., Leimkühler, Silke

Journal:

JBIC Journal of Biological Inorganic Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 645 KB

english, 2015

7

Enzyme cascade reactions: synthesis of furandicarboxylic acid (FDCA) and carboxylic acids using oxidases in tandem

McKenna, Shane M., Leimkühler, Silke, Herter, Susanne, Turner, Nicholas J., Carnell, Andrew J.

Journal:

Green Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 272 KB

english, 2015

8

Bacterial molybdoenzymes: old enzymes for new purposes

Leimkühler, Silke, Iobbi-Nivol, Chantal, Giudici-Orticoni, Marie-Therese

Journal:

FEMS Microbiology Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2015

9

Shared Sulfur Mobilization Routes for tRNA Thiolation and Molybdenum Cofactor Biosynthesis in Prokaryotes and Eukaryotes

Leimkühler, Silke, Bühning, Martin, Beilschmidt, Lena

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 5.84 MB

english, 2017

10

The Regulation of Moco Biosynthesis and Molybdoenzyme gene expression by Molybdenum and Iron in Bacteria

Zupok, Arkadiusz, Iobbi-Nivol, Chantal, Mejean, Vincent, Leimkühler, Silke

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2019

11

A Crystallographic and Mo K-Edge XAS Study of Molybdenum Oxo Bis-, Mono-, and Non-Dithiolene Complexes – First-Sphere Coordination Geometry and Noninnocence of Ligands

Prinson P. Samuel, Sebastian Horn, Alexander Döring, Kajsa G. V. Havelius, Stefan Reschke, Silke Leimkühler, Michael Haumann, Carola Schulzke

Journal:

European Journal of Inorganic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 634 KB

english, 2011

12

The history of the discovery of the molybdenum cofactor and novel aspects of its biosynthesis in bacteria

Silke Leimkühler, Margot M. Wuebbens, K.V. Rajagopalan

Journal:

Coordination Chemistry Reviews

Année:

2011

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2011

13

Sulfite biosensor based on osmium redox polymer wired sulfite oxidase

Roberto Spricigo, Claudia Richter, Silke Leimkühler, Lo Gorton, Frieder W. Scheller, Ulla Wollenberger

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Année:

2010

Langue:

english

Fichier:

PDF, 408 KB

english, 2010

14

Studies on the mechanism of action of xanthine oxidase

Eun-Young Choi, Amy L. Stockert, Silke Leimkühler, Russ Hille

Journal:

Journal of Inorganic Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 298 KB

english, 2004

15

Xanthine dehydrogenase from the phototrophic purple bacterium Rhodobacter capsulatus is more similar to its eukaryotic counterparts than to prokaryotic molybdenum enzymes

Silke Leimkühler, Monika Kern, Peter S. Solomon, Alastair G. McEwan, Günter Schwarz, Ralf R. Mendel, Werner Klipp

Journal:

Molecular Microbiology

Année:

1998

Langue:

english

Fichier:

PDF, 2.14 MB

english, 1998

16

Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains

Petra Hänzelmann, Jan U. Dahl, Jochen Kuper, Alexander Urban, Ursula Müller-Theissen, Silke Leimkühler, Hermann Schindelin

Journal:

Protein Science

Année:

2009

Langue:

english

Fichier:

PDF, 618 KB

english, 2009

17

Electrocatalytic sulfite biosensor with human sulfite oxidase co-immobilized with cytochrome c in a polyelectrolyte-containing multilayer

Roberto Spricigo, Roman Dronov, Fred Lisdat, Silke Leimkühler, Frieder W. Scheller, Ulla Wollenberger

Journal:

Analytical and Bioanalytical Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 255 KB

english, 2009

18

Ten novel mutations in the molybdenum cofactor genesMOCS1 andMOCS2 and in vitro characterization of aMOCS2 mutation that abolishes the binding ability of molybdopterin synthase

Silke Leimkühler, Mathilde Charcosset, Philippe Latour, Claude Dorche, Soledad Kleppe, Fernando Scaglia, Irmina Szymczak, Petra Schupp, Rita Hahnewald, Jochen Reiss

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 278 KB

english, 2005

19

The molybdenum cofactor biosynthesis protein MobA from Rhodobacter capsulatus is required for the activity of molybdenum enzymes containing MGD, but not for xanthine dehydrogenase harboring the MPT cofactor

Silke Leimkühler, Werner Klipp

Journal:

FEMS Microbiology Letters

Année:

1999

Langue:

english

Fichier:

PDF, 205 KB

english, 1999

20

Molybdate-dependent expression of dimethylsulfoxide reductase in Rhodobacter capsulatus

Peter S. Solomon, Anthony L. Shaw, Michael D. Young, Silke Leimkuhler, Graeme R. Hanson, Werner Klipp, Alastair G. McEwan

Journal:

FEMS Microbiology Letters

Année:

2000

Langue:

english

Fichier:

PDF, 247 KB

english, 2000

21

Site-directed mutagenesis of the active site loop of the rhodanese-like domain of the human molybdopterin synthase sulfurase MOCS3 : Major differences in substrate specificity between eukaryotic and bacterial homologs

Karsten Krepinsky, Silke Leimkühler

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 980 KB

english, 2007

22

Heavy metal ions inhibit molybdoenzyme activity by binding to the dithiolene moiety of molybdopterin in Escherichia coli

Meina Neumann, Silke Leimkühler

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 385 KB

english, 2008

23

A periplasmic aldehyde oxidoreductase represents the first molybdopterin cytosine dinucleotide cofactor containing molybdo-flavoenzyme from Escherichia coli

Meina Neumann, Gerd Mittelstädt, Chantal Iobbi-Nivol, Miguel Saggu, Friedhelm Lendzian, Peter Hildebrandt, Silke Leimkühler

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 332 KB

english, 2009

24

Layer-by-Layer Arrangement by Protein−Protein Interaction of Sulfite Oxidase and Cytochrome c Catalyzing Oxidation of Sulfite

Dronov, Roman, Kurth, Dirk G., Möhwald, Helmuth, Spricigo, Roberto, Leimkühler, Silke, Wollenberger, Ulla, Rajagopalan, K. V., Scheller, Frieder W., Lisdat, Fred

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 62 KB

english, 2008

25

Semimetallic TiO2 nanotubes: new interfaces for bioelectrochemical enzymatic catalysis

Sarauli, David, Riedel, Marc, Wettstein, Christoph, Hahn, Robert, Stiba, Konstanze, Wollenberger, Ulla, Leimkühler, Silke, Schmuki, Patrik, Lisdat, Fred

Journal:

Journal of Materials Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 325 KB

english, 2012

26

Thin films of substituted polyanilines: interactions with biomolecular systems

Sarauli, David, Xu, Chenggang, Dietzel, Birgit, Stiba, Konstanze, Leimkühler, Silke, Schulz, Burkhard, Lisdat, Fred

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 707 KB

english, 2012

27

Crystal Structures of the Active and Alloxanthine-Inhibited Forms of Xanthine Dehydrogenase from Rhodobacter capsulatus

James J Truglio, Karsten Theis, Silke Leimkühler, Roberto Rappa, K.V Rajagopalan, Caroline Kisker

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 634 KB

english, 2002

28

Molybdenum Cofactor Biosynthesis in Humans: Identification of a Persulfide Group in the Rhodanese-like Domain of MOCS3 by Mass Spectrometry†

Matthies, Andreas, Nimtz, Manfred, Leimkühler, Silke

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 384 KB

english, 2005

29

The cysteine-desulfurase IscS promotes the production of the rhodanese RhdA in the persulfurated form

Fabio Forlani, Angelo Cereda, Andrea Freuer, Manfred Nimtz, Silke Leimkühler, Silvia Pagani

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 138 KB

english, 2005

30

A novel MOCS2 mutation reveals coordinated expression of the small and large subunit of molybdopterin synthase

Rita Hahnewald, Silke Leimkühler, Antonia Vilaseca, Cecile Acquaviva-Bourdain, Ulrike Lenz, Jochen Reiss

Journal:

Molecular Genetics and Metabolism

Année:

2006

Langue:

english

Fichier:

PDF, 218 KB

english, 2006

31

Molybdate-dependent expression of dimethylsulfoxide reductase in Rhodobacter capsulatus

Peter S. Solomon, Anthony L. Shaw, Michael D. Young, Silke Leimkuhler, Graeme R. Hanson, Werner Klipp, Alastair G. McEwan

Journal:

FEMS Microbiology Letters

Année:

2000

Langue:

english

Fichier:

PDF, 250 KB

english, 2000

32

The molybdenum cofactor biosynthesis protein MobA from Rhodobacter capsulatus is required for the activity of molybdenum enzymes containing MGD, but not for xanthine dehydrogenase harboring the MPT cofactor

Silke Leimkühler, Werner Klipp

Journal:

FEMS Microbiology Letters

Année:

1999

Langue:

english

Fichier:

PDF, 208 KB

english, 1999

33

Catalytic Electrochemistry of Xanthine Dehydrogenase

Kalimuthu, Palraj, Leimkühler, Silke, Bernhardt, Paul V.

Journal:

Journal of Physical Chemistry B

Année:

2012

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2012

34

Complementary Surface-Enhanced Resonance Raman Spectroscopic Biodetection of Mixed Protein Solutions by Chitosan- and Silica-Coated Plasmon-Tuned Silver Nanoparticles

Sivanesan, Arumugam, Kalaivani, Govindasamy, Fischer, Anna, Stiba, Konstanze, Leimkühler, Silke, Weidinger, Inez M.

Journal:

Analytical Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 358 KB

english, 2012

35

A Biosensor for Aromatic Aldehydes Comprising the Mediator Dependent PaoABC-Aldehyde Oxidoreductase

Badalyan, Artavazd, Neumann-Schaal, Meina, Leimkühler, Silke, Wollenberger, Ulla

Journal:

Electroanalysis

Année:

2013

Langue:

english

Fichier:

PDF, 259 KB

english, 2013

36

Tellurite resistance genetrgBconfers copper tolerance toRhodobacter capsulatus

Corinna Rademacher, Marie-Christine Hoffmann, Jan-Wilm Lackmann, Roman Moser, Yvonne Pfänder, Silke Leimkühler, Franz Narberhaus, Bernd Masepohl

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 634 KB

english, 2012

37

Human sulfite oxidase electrochemistry on gold nanoparticles modified electrode

Frasca, Stefano, Rojas, Oscar, Salewski, Johannes, Neumann, Bettina, Stiba, Konstanze, Weidinger, Inez M., Tiersch, Brigitte, Leimkühler, Silke, Koetz, Joachim, Wollenberger, Ulla

Journal:

Bioelectrochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 954 KB

english, 2012

38

Low-Potential Amperometric Enzyme Biosensor for Xanthine and Hypoxanthine

Kalimuthu, Palraj, Leimkühler, Silke, Bernhardt, Paul V.

Journal:

Analytical Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 863 KB

english, 2012

39

Tunable Electric Field Enhancement and Redox Chemistry on TiO 2 Island Films via Covalent Attachment to Ag or Au Nanostructures

Sivanesan, Arumugam, Ly, Khoa H., Adamkiewicz, Witold, Stiba, Konstanze, Leimkühler, Silke, Weidinger, Inez M.

Journal:

The Journal of Physical Chemistry C

Année:

2013

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2013

40

The oxygen-tolerant and NAD + -dependent formate dehydrogenase from Rhodobacter capsulatus is able to catalyze the reduction of CO 2 to formate

Hartmann, Tobias, Leimkühler, Silke

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 362 KB

english, 2013

41

Molybdenum enzymes, their maturation and molybdenum cofactor biosynthesis in Escherichia coli

Iobbi-Nivol, Chantal, Leimkühler, Silke

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2013

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2013

42

Analysis of the interaction of the molybdenum hydroxylase PaoABC from Escherichia coli with positively and negatively charged metal complexes

Badalyan, Artavazd, Yoga, Etienne Galemou, Schwuchow, Viola, Pöller, Sascha, Schuhmann, Wolfgang, Leimkühler, Silke, Wollenberger, Ulla

Journal:

Electrochemistry Communications

Année:

2013

Langue:

english

Fichier:

PDF, 344 KB

english, 2013

43

The chaperone FdsC for Rhodobacter capsulatus formate dehydrogenase binds the bis-molybdopterin guanine dinucleotide cofactor

Böhmer, Nadine, Hartmann, Tobias, Leimkühler, Silke

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 887 KB

english, 2014

44

Bioelectrocatalysis at mesoporous antimony doped tin oxide electrodes—Electrochemical characterization and direct enzyme communication

Frasca, Stefano, Molero Milan, Anabel, Guiet, Amandine, Goebel, Caren, Pérez-Caballero, Fernando, Stiba, Konstanze, Leimkühler, Silke, Fischer, Anna, Wollenberger, Ulla

Journal:

Electrochimica Acta

Année:

2013

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2013

45

Ketoxime Coupling of p -Acetylphenylalanine at Neutral pH for Site-Directed Spin Labeling of Human Sulfite Oxidase

Hahn, Aaron, Reschke, Stefan, Leimkühler, Silke, Risse, Thomas

Journal:

Journal of Physical Chemistry B

Année:

2014

Langue:

english

Fichier:

PDF, 339 KB

english, 2014

46

Different inhibitory potency of febuxostat towards mammalian and bacterial xanthine oxidoreductases: insight from molecular dynamics

Kikuchi, Hiroto, Fujisaki, Hiroshi, Furuta, Tadaomi, Okamoto, Ken, Leimkühler, Silke, Nishino, Takeshi

Journal:

Scientific Reports

Année:

2012

Langue:

english

Fichier:

PDF, 614 KB

english, 2012

47

The role of FeS clusters for molybdenum cofactor biosynthesis and molybdoenzymes in bacteria

Yokoyama, Kenichi, Leimkühler, Silke

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 3.56 MB

english, 2015

48

Protein Film Voltammetry of Rhodobacter Capsulatus Xanthine Dehydrogenase

Aguey-Zinsou, Kondo François, Bernhardt, Paul V., Leimkühler, Silke

Journal:

Journal of the American Chemical Society

Année:

2003

Langue:

english

Fichier:

PDF, 144 KB

english, 2003

49

Role of the C-Terminal Gly-Gly Motif of Escherichia Coli MoaD, a Molybdenum Cofactor Biosynthesis Protein with a Ubiquitin Fold †

Schmitz, Jennifer, Wuebbens, Margot M., Rajagopalan, K. V., Leimkühler, Silke

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 116 KB

english, 2007

50

Pyranopterin Dithiolene Distortions Relevant to Electron Transfer in Xanthine Oxidase/Dehydrogenase

Dong, Chao, Yang, Jing, Leimkühler, Silke, Kirk, Martin L.

Journal:

Inorganic Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 828 KB

english, 2014